Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.34 |
| ▸ | ITGAL | P20701 | 4/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967535 | 0.93 | FAAH (0.35) | FAAHCNR2ERCC5FEN1ITGB2 | |
| SCHEMBL6975892 | 0.91 | ALDH1A1 (0.36) | FAAHCNR2ERCC5FEN1ITGB2 | |
| SCHEMBL6956997 | 0.89 | FAAH (0.36) | FAAHCNR2ERCC5FEN1ITGB2 | |
| SCHEMBL6974151 | 0.86 | FAAH (0.36) | FAAHERCC5FEN1ITGB2ICAM1 | |
| SCHEMBL6962108 | 0.86 | TDP1 (0.37) | — | |
| SCHEMBL6972767 | 0.85 | FAAH (0.35) | FAAHERCC5FEN1ITGB2ICAM1 | |
| SCHEMBL6969539 | 0.82 | GRIN1 (0.39) | — | |
| SCHEMBL6972940 | 0.81 | FAAH (0.35) | FAAHCNR2ERCC5FEN1ITGB2 | |
| SCHEMBL6960983 | 0.81 | ENPP2 (0.32) | — | |
| SCHEMBL6973511 | 0.81 | S1PR3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |