Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.34 |
| ▸ | ITGAL | P20701 | 5/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974151 | 0.92 | FAAH (0.36) | FAAHITGB2ICAM1ITGALERCC5 | |
| SCHEMBL6960043 | 0.91 | FAAH (0.35) | FAAHITGB2ICAM1ITGALERCC5 | |
| SCHEMBL6967887 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL6967535 | 0.87 | FAAH (0.35) | FAAHITGB2ICAM1ITGALERCC5 | |
| SCHEMBL7083375 | 0.86 | FAAH (0.34) | FAAHITGB2ICAM1ITGALERCC5 | |
| SCHEMBL6975892 | 0.85 | ALDH1A1 (0.36) | FAAHITGB2ICAM1ITGALERCC5 | |
| SCHEMBL6968913 | 0.85 | FAAH (0.36) | FAAHITGB2ICAM1ITGALERCC5 | |
| SCHEMBL6974966 | 0.85 | GRIN1 (0.36) | — | |
| SCHEMBL6967988 | 0.84 | ENPP2 (0.35) | — | |
| SCHEMBL6967033 | 0.84 | ENPP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |