Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955809 | 0.86 | HPGDS (0.39) | KDM4CKDM5BHPGDSCYP2E1CYP3A4 | |
| SCHEMBL6973877 | 0.85 | CYP3A4 (0.45) | KDM4CKDM5BHPGDSCYP2E1CYP3A4 | |
| SCHEMBL6974237 | 0.82 | CDK5 (0.51) | L3MBTL1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30741761 | 0.81 | HPGDS (0.50) | KDM4CKDM5BHPGDSCYP2E1CYP3A4 | |
| SCHEMBL6968287 | 0.79 | NR1H2 (0.38) | KDM4CKDM5B | |
| SCHEMBL6952807 | 0.77 | SIGMAR1 (0.45) | KDM4CKDM5BHPGDSCYP2E1CYP3A4 | |
| SCHEMBL6968013 | 0.75 | KDM4C (0.40) | KDM4CKDM5BHPGDSL3MBTL1 | |
| SCHEMBL5755514 | 0.74 | NPC1 (0.60) | KDM4CKDM5BHPGDSCYP2E1CYP3A4 | |
| SCHEMBL6965586 | 0.72 | THRB (0.39) | CYP2A6CYP2B6LMNAMAPK1GAA | |
| SCHEMBL6972346 | 0.72 | PHF8 (0.38) | KDM4CKDM5BHPGDSCYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |