Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955809 | 0.85 | HPGDS (0.39) | CYP19A1SIGMAR1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL6973877 | 0.84 | CYP3A4 (0.45) | LTA4HCYP19A1CYP11B1CYP11B2POLB | |
| SCHEMBL6972535 | 0.82 | KDM4C (0.38) | POLBL3MBTL1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30741761 | 0.80 | HPGDS (0.50) | CDK5CDK5R1CYP19A1SIGMAR1CYP11B1 | |
| SCHEMBL6952807 | 0.76 | SIGMAR1 (0.45) | CYP19A1SIGMAR1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL6965586 | 0.74 | THRB (0.39) | LTA4HCYP19A1CYP11B1CYP11B2HTT | |
| SCHEMBL6972346 | 0.74 | PHF8 (0.38) | CDK5CDK5R1CYP19A1SIGMAR1ALDH1A1 | |
| SCHEMBL4840104 | 0.73 | HPGDS (0.58) | CDK5CDK5R1SIGMAR1CYP11B1CYP11B2 | |
| SCHEMBL5755079 | 0.73 | NPC1 (0.60) | CDK5CDK5R1CYP19A1CYP11B1NPC1 | |
| SCHEMBL13824975 | 0.73 | CDK5 (0.46) | CDK5CDK5R1CYP19A1CYP11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |