Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 5/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697528 | 0.80 | IDH1 (0.34) | IDH1SMN1; SMN2 | |
| SCHEMBL1573428 | 0.79 | APAF1 (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4008767 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL1574142 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL1573270 | 0.76 | KMT2A (0.38) | SMN1; SMN2ALDH1A1PTGES | |
| SCHEMBL696567 | 0.76 | IDH1 (0.42) | IDH1 | |
| SCHEMBL4014276 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL1573396 | 0.74 | ITGB3 (0.37) | SMN1; SMN2ALDH1A1PTGES | |
| SCHEMBL696942 | 0.74 | LDHA (0.38) | ALDH1A1 | |
| SCHEMBL4007502 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |