Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.85 |
| ▸ | MMP9 | P14780 | 10/20 | 0.85 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.85 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | MMP1 | P03956 | 1/20 | 0.74 |
| ▸ | MMP3 | P08254 | 1/20 | 0.74 |
| ▸ | MMP7 | P09237 | 1/20 | 0.74 |
| ▸ | MMP13 | P45452 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188026 | 1.00 | MMP2 (0.85) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL697591 | 1.00 | MMP2 (0.85) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL6545297 | 0.92 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL1920507 | 0.92 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL32691761 | 0.92 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL8912956 | 0.91 | L3MBTL1 (0.78) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL3009406 | 0.90 | MMP2 (0.92) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL14218255 | 0.90 | MMP2 (0.79) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL8063645 | 0.90 | TDP1 (0.78) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL697477 | 0.90 | MMP2 (0.79) | MMP2MMP9ADAMTS4ADAMTS5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS INC (US) | 2019-05-09 | — | — | US | claimed |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS, INC. | 2012-05-31 | — | — | US | claimed |
| EP-1457487-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE CIS-PIPERIDINE DERIVATIVES | Toray Fine Chemicals Co., Ltd. (JP) | 2004-09-15 | — | — | EP | claimed |
| US-20040171836-A1 | Method for producing optical-active cis-piperidine derivatives | TORAY FINE CHEMICALS CO., LTD., A CORPORATION OF JAPAN, (JP) | 2004-09-02 | — | — | US | claimed |
| US-20040062773-A1 | Compositions for the delivery of antigens | EMISPHERE TECHNOLOGIES INC. | 2004-04-01 | — | — | US | claimed |
| EP-0784469-B1 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | EMISPHERE TECH INC (US) | 2004-03-24 | — | — | EP | claimed |
| US-6610329-B2 | Using acylated amino acid as carrier | EMISPHERE TECHNOLOGIES INC. | 2003-08-26 | — | — | US | claimed |
| US-20020001591-A1 | Compositions for the delivery of antigens | EMISPHERE TECHNOLOGIES, INC. | 2002-01-03 | — | — | US | claimed |
| US-5958457-A | MIXTURES OF ANTIGENS WITH ADJUVANTS AND ACYLATED AMINO ACIDS OR SALTS, POLYMERS OR SULFONATED AMINO ACIDS | EMISPHERE TECHNOLOGIES, INC. (US) | 1999-09-28 | — | — | US | claimed |
| EP-0784469-A4 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | EMISPHERE TECH INC (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0784469-A1 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | Emisphere Technologies, Inc. (US) | 1997-07-23 | — | — | EP | claimed |
| WO-1996012474-A1 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | EMISPHERE TECHNOLOGIES, INC. (US) | 1996-05-02 | — | — | WO | claimed |
| US-11897843-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | REUTER CHEMISCHE APPARATEBAU KG | 2024-02-13 | — | — | US | disclosed |
| EP-4289819-A2 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | Reuter Chemische Apparatebau e.K. (DE) | 2023-12-13 | — | — | EP | disclosed |
| US-20230008387-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2023-01-12 | — | — | US | disclosed |
| US-11472770-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | REUTER CHEMISCHE APPARATEBAU KG | 2022-10-18 | — | — | US | disclosed |
| EP-0602028-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | PHARNO WEDROPHARM GMBH (DE) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993005014-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO-WEDROPHARM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |
| US-5045540-A | Amide or urea compounds containing imidazole groups | WARNER-LAMBERT CO. (US) | 1991-09-03 | — | — | US | disclosed |
| US-5041552-A | Treatment of hypertension, heart failure, glaucoma and hyperaldosteronism | WARNER-LAMBERT COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171836-A1 | Method for producing optical-active cis-piperidine derivatives | TYR, DDC, TARBP1 | MMP2 1206/4885MMP9 1373/4885ADAMTS4 2548/4885 |
| US-20230008387-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | NPEPPS, AASDHPPT, DNPEP | MMP2 4358/4885MMP9 4567/4885ADAMTS4 4756/4885 |
| US-11472770-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | NPEPPS, AASDHPPT, DNPEP | MMP2 4358/4885MMP9 4567/4885ADAMTS4 4756/4885 |
| US-20020001591-A1 | Compositions for the delivery of antigens | CD47, CD74, LY96 | MMP2 2444/4885MMP9 2979/4885ADAMTS4 3212/4885 |
| US-20040062773-A1 | Compositions for the delivery of antigens | CD47, CD74, LY96 | MMP2 2444/4885MMP9 2979/4885ADAMTS4 3212/4885 |
| US-11897843-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | NPEPPS, AASDHPPT, DNPEP | MMP2 4338/4885MMP9 4597/4885ADAMTS4 4764/4885 |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | TPH1, TPH2, HTR1B | MMP2 3493/4885MMP9 3356/4885ADAMTS4 3693/4885 |
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | TPH1, TPH2, HTR1B | MMP2 3524/4885MMP9 3464/4885ADAMTS4 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.