Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970267 | 0.82 | POLB (0.46) | KMT2AMEN1CYP2C19POLBKDM4E | |
| SCHEMBL7464135 | 0.75 | ADRA1A (0.44) | KMT2AMEN1ALDH1A1TP53MAPT | |
| SCHEMBL6976119 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1RAB9AATMPOLB | |
| SCHEMBL6093231 | 0.70 | KDM4E (0.77) | KMT2APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12804001 | 0.68 | TSPO (0.54) | KMT2AMEN1RAB9AATMCYP2C19 | |
| SCHEMBL6975022 | 0.68 | MMP2 (0.51) | — | |
| SCHEMBL14158200 | 0.67 | MEN1 (0.53) | KMT2AMEN1RAB9AATMCYP2C19 | |
| SCHEMBL314589 | 0.67 | TSHR (0.75) | KMT2AMEN1RAB9AATMKDM4E | |
| SCHEMBL608528 | 0.67 | ALDH1A1 (0.76) | KMT2APOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12804494 | 0.67 | NOD2 (0.54) | KMT2AMEN1RAB9AATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |