Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979149 | 0.87 | PARP1 (0.40) | USP14NOTUMALDH1A1PARP1RAB9A | |
| SCHEMBL6979942 | 0.85 | TSHR (0.38) | ALDH1A1PARP1RAB9ANPC1MAPT | |
| SCHEMBL6982692 | 0.85 | L3MBTL1 (0.38) | USP14NOTUMALDH1A1RAB9ANPC1 | |
| SCHEMBL6985399 | 0.84 | NOTUM (0.36) | USP14NOTUMALDH1A1RAB9ANPC1 | |
| SCHEMBL6987767 | 0.83 | TP53 (0.42) | ALDH1A1USP2HSD17B10L3MBTL1GAA | |
| SCHEMBL6985613 | 0.83 | CCR5 (0.37) | USP14NOTUMALDH1A1RAB9ANPC1 | |
| SCHEMBL6986000 | 0.81 | NR3C1 (0.36) | USP14NOTUMALDH1A1RAB9ANPC1 | |
| SCHEMBL6980758 | 0.81 | NOTUM (0.42) | USP14NOTUMALDH1A1RAB9ANPC1 | |
| SCHEMBL6984734 | 0.80 | AVPR2 (0.36) | ALDH1A1PARP1RAB9ANPC1MAPT | |
| SCHEMBL6977212 | 0.78 | TRPM8 (0.39) | USP14NOTUMALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |