Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.33 |
| ▸ | OXTR | P30559 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987767 | 0.87 | TP53 (0.42) | NR3C1ALDH1A1LMNAGAAL3MBTL1 | |
| SCHEMBL6985993 | 0.85 | NR3C1 (0.46) | NR3C1USP14MAPTALDH1A1MAPK1 | |
| SCHEMBL6982692 | 0.82 | L3MBTL1 (0.38) | NR3C1USP14MAPTNOTUMALDH1A1 | |
| SCHEMBL6985399 | 0.82 | NOTUM (0.36) | USP14MAPTAVPR2OXTRAVPR1A | |
| SCHEMBL6979151 | 0.81 | USP14 (0.35) | USP14MAPTNOTUMALDH1A1NPC1 | |
| SCHEMBL6985613 | 0.81 | CCR5 (0.37) | USP14MAPTNOTUMALDH1A1NPC1 | |
| SCHEMBL7407619 | 0.80 | MAPT (0.34) | NR3C1MAPTALDH1A1GAA | |
| SCHEMBL6978045 | 0.80 | ALDH1A1 (0.35) | NR3C1USP14MAPTAVPR2NOTUM | |
| SCHEMBL6984734 | 0.79 | AVPR2 (0.36) | NR3C1MAPTAVPR2OXTRAVPR1A | |
| SCHEMBL6980758 | 0.79 | NOTUM (0.42) | USP14MAPTAVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |