Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982692 | 0.90 | L3MBTL1 (0.38) | NOTUMYAP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL6985609 | 0.85 | NOTUM (0.39) | CCR5NOTUMYAP1SMN1; SMN2NPC1 | |
| SCHEMBL6985399 | 0.85 | NOTUM (0.36) | NOTUMPTGER4YAP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6987767 | 0.84 | TP53 (0.42) | L3MBTL1ALDH1A1USP2LMNAHSD17B10 | |
| SCHEMBL6979151 | 0.83 | USP14 (0.35) | NOTUMYAP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL6980758 | 0.82 | NOTUM (0.42) | NOTUMPTGER4L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL6986000 | 0.81 | NR3C1 (0.36) | NOTUML3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL6979172 | 0.79 | KDM1A (0.41) | SMN1; SMN2NPC1MAPTMAPK1RAB9A | |
| SCHEMBL6980097 | 0.79 | KDM1A (0.37) | PTGER4SMN1; SMN2NPC1MAPTMAPK1 | |
| SCHEMBL6984169 | 0.79 | KDM1A (0.38) | PTGER4YAP1SMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |