Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981595 | 0.90 | LTB4R2 (0.46) | ALDH1A1SMN1; SMN2MAPTNPC1MAPK1 | |
| SCHEMBL6982692 | 0.88 | L3MBTL1 (0.38) | NOTUML3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6986008 | 0.88 | MEN1 (0.39) | ALDH1A1SMN1; SMN2MAPTNPC1MAPK1 | |
| SCHEMBL6985399 | 0.86 | NOTUM (0.36) | NOTUML3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6980751 | 0.85 | NOTUM (0.44) | NOTUML3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6986002 | 0.84 | RXRA (0.45) | ALDH1A1SMN1; SMN2MAPTNPC1MAPK1 | |
| SCHEMBL6987767 | 0.82 | TP53 (0.42) | L3MBTL1ALDH1A1LMNAGAAUSP2 | |
| SCHEMBL6985613 | 0.82 | CCR5 (0.37) | NOTUML3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6987632 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTNPC1MAPK1 | |
| SCHEMBL6978045 | 0.81 | ALDH1A1 (0.35) | NOTUML3MBTL1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |