Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984821 | 0.90 | TUBB4A (0.40) | PKMTP53METAP2MAPTMEN1 | |
| SCHEMBL6983505 | 0.87 | NR3C1 (0.42) | PKMALDH1A1TP53MAPTMEN1 | |
| SCHEMBL6985322 | 0.87 | GAA (0.41) | PKMALDH1A1TP53METAP2MAPT | |
| SCHEMBL6979366 | 0.85 | NR3C1 (0.54) | PKMTP53MAPTMEN1KMT2A | |
| SCHEMBL7411038 | 0.83 | PKM (0.43) | PKMALDH1A1TP53MAPTMEN1 | |
| SCHEMBL6987605 | 0.83 | SLC40A1 (0.38) | PKMTP53METAP2MAPTMEN1 | |
| SCHEMBL6984843 | 0.83 | GAA (0.43) | PKMALDH1A1METAP2MEN1KMT2A | |
| SCHEMBL6985749 | 0.83 | ALDH1A1 (0.48) | PKMALDH1A1TP53MAPTMEN1 | |
| SCHEMBL6984039 | 0.80 | TP53 (0.45) | PKMALDH1A1TP53MAPTLMNA | |
| SCHEMBL7414191 | 0.80 | PKM (0.42) | PKMALDH1A1TP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |