Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 4/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985320 | 0.84 | F2 (0.44) | MGAT2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL6985322 | 0.82 | GAA (0.41) | ALDH1A1GAAARNR3C1LSS | |
| SCHEMBL6983682 | 0.81 | TP53 (0.49) | MGAT2HTR2AARNR3C1 | |
| SCHEMBL6983048 | 0.78 | NAMPT (0.41) | ALDH1A1ARNR3C1PTGES2THRB | |
| SCHEMBL6985371 | 0.76 | NR3C1 (0.44) | SLC22A12ALDH1A1GAAARNR3C1 | |
| SCHEMBL6981761 | 0.76 | LIMK2 (0.40) | ALDH1A1HPGDARNR3C1THRB | |
| SCHEMBL6980541 | 0.75 | HSD17B10 (0.48) | ALDH1A1GAAARNR3C1HSD17B10 | |
| SCHEMBL6982764 | 0.74 | FPR1 (0.43) | SLC22A12ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL7408050 | 0.74 | TP53 (0.40) | GLO1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL6985749 | 0.74 | ALDH1A1 (0.48) | ALDH1A1GAANR3C1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |