Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986113 | 0.87 | AGTR2 (0.41) | MEN1KMT2AHSD17B10SMN1; SMN2USP2 | |
| SCHEMBL6988584 | 0.85 | USP2 (0.43) | MEN1KMT2ASMN1; SMN2USP2AGTR2 | |
| SCHEMBL6981026 | 0.85 | AGTR2 (0.40) | MEN1KMT2AHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL6984622 | 0.83 | AGTR2 (0.39) | KMT2AHSD17B10SMN1; SMN2AGTR2LMNA | |
| SCHEMBL6986283 | 0.81 | HTR2C (0.42) | AGTR2 | |
| SCHEMBL6983767 | 0.81 | DRD4 (0.41) | MEN1KMT2AHSD17B10SMN1; SMN2USP2 | |
| SCHEMBL6986237 | 0.80 | AGTR2 (0.39) | MEN1KMT2AAGTR2KDM4EGAA | |
| SCHEMBL6988437 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL6981802 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AP2RX3HSD17B10SMN1; SMN2 | |
| SCHEMBL6984282 | 0.78 | HSD17B10 (0.43) | MEN1KMT2AHSD17B10SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |