Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985626 | 0.89 | SLC5A1 (0.43) | SMN1; SMN2SLC5A1 | |
| SCHEMBL6985081 | 0.88 | SLC5A1 (0.42) | ALDH1A1SMN1; SMN2SLC5A1ADORA3 | |
| SCHEMBL6979355 | 0.83 | SOAT2 (0.42) | SLC5A1 | |
| SCHEMBL6984285 | 0.81 | PTGS2 (0.40) | GAAALDH1A1SLC5A1ADORA3 | |
| SCHEMBL6986371 | 0.79 | ALDH1A1 (0.41) | GAAALDH1A1MAPK1KMT2A | |
| SCHEMBL6987355 | 0.77 | ALDH1A1 (0.38) | GAAALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL6986812 | 0.75 | ALDH1A1 (0.40) | GAALMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6988584 | 0.75 | USP2 (0.43) | LMNAALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL6985846 | 0.74 | BCL2 (0.41) | GAAALDH1A1SMN1; SMN2SLC5A1KMT2A | |
| SCHEMBL6538384 | 0.74 | TP53 (0.44) | GRM5LMNAADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |