Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 14/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985081 | 0.90 | SLC5A1 (0.42) | SLC5A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL6983748 | 0.89 | GRM5 (0.46) | SLC5A1SMN1; SMN2 | |
| SCHEMBL6979355 | 0.85 | SOAT2 (0.42) | SLC5A1 | |
| SCHEMBL6984285 | 0.82 | PTGS2 (0.40) | SLC5A1 | |
| SCHEMBL6986371 | 0.81 | ALDH1A1 (0.41) | NPC1RAB9ATSHRHTTTP53 | |
| SCHEMBL6987355 | 0.79 | ALDH1A1 (0.38) | MAPTKDM4ENPC1PKMRAB9A | |
| SCHEMBL6986605 | 0.78 | HTT (0.48) | MAPTSMN1; SMN2TSHRHTT | |
| SCHEMBL6986812 | 0.77 | ALDH1A1 (0.40) | MAPTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6985846 | 0.76 | BCL2 (0.41) | SLC5A1MAPTSMN1; SMN2TSHRHTT | |
| SCHEMBL6986113 | 0.76 | AGTR2 (0.41) | SMN1; SMN2HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |