Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 4/20 | 0.40 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986437 | 0.85 | PTGER4 (0.41) | ATMFPR1FPR2HDAC1HDAC8 | |
| SCHEMBL6985381 | 0.85 | MMP1 (0.45) | ATMFPR1FPR2KDM1AHDAC1 | |
| SCHEMBL6986817 | 0.84 | THRB (0.42) | ATMFPR1FPR2HDAC1HDAC8 | |
| SCHEMBL6977736 | 0.84 | CHRM3 (0.40) | ATMFPR1FPR2KDM1AALDH1A1 | |
| SCHEMBL6980994 | 0.82 | RXRA (0.43) | ATMFPR1FPR2HDAC6ALDH1A1 | |
| SCHEMBL6985566 | 0.82 | PARP14 (0.40) | ATMFPR1FPR2ALDH1A1MEN1 | |
| SCHEMBL6982945 | 0.81 | NR3C1 (0.36) | ATMFPR1FPR2ALDH1A1HPGD | |
| SCHEMBL6984459 | 0.80 | FPR1 (0.44) | FPR1FPR2HDAC1HDAC8HDAC6 | |
| SCHEMBL6979727 | 0.80 | TSHR (0.40) | FPR1FPR2HDAC1HDAC8HDAC6 | |
| SCHEMBL6978202 | 0.80 | ALDH1A1 (0.37) | ATMFPR1FPR2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |