Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986823 | 0.92 | MGLL (0.60) | MGLLNTRK1PTGS2MALT1 | |
| SCHEMBL6988945 | 0.92 | MGLL (0.49) | MGLLPTGS2MALT1RPA1 | |
| SCHEMBL7090364 | 0.91 | MGLL (0.48) | MGLLPTGS2MALT1RPA1 | |
| SCHEMBL6988238 | 0.86 | MGLL (0.51) | MGLL | |
| SCHEMBL6986113 | 0.86 | AGTR2 (0.41) | MGLL | |
| SCHEMBL6986523 | 0.81 | HTT (0.42) | — | |
| SCHEMBL6988584 | 0.80 | USP2 (0.43) | MGLL | |
| SCHEMBL7141579 | 0.80 | CACNB4 (0.47) | MGLL | |
| SCHEMBL6986371 | 0.77 | ALDH1A1 (0.41) | RPA1 | |
| SCHEMBL6985626 | 0.76 | SLC5A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |