Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986647 | 0.92 | MGLL (0.50) | MGLLNTRK1PTGS2MALT1 | |
| SCHEMBL6988945 | 0.92 | MGLL (0.49) | MGLLHPGDALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL7090364 | 0.91 | MGLL (0.48) | MGLLHPGDALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL6988238 | 0.86 | MGLL (0.51) | MGLLKDM4EHPGDALDH1A1LMNA | |
| SCHEMBL6984622 | 0.81 | AGTR2 (0.39) | MGLLALDH1A1SMN1; SMN2BRD4LMNA | |
| SCHEMBL6987595 | 0.81 | TDP1 (0.42) | MGLLKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6988584 | 0.80 | USP2 (0.43) | MGLLALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL6986113 | 0.78 | AGTR2 (0.41) | MGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6986889 | 0.77 | L3MBTL1 (0.40) | MGLLKDM4EALDH1A1RAB9ALMNA | |
| SCHEMBL6986371 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |