Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988945 | 0.99 | MGLL (0.49) | MGLLMALT1CNR1CNR2ALDH1A1 | |
| SCHEMBL6986647 | 0.91 | MGLL (0.50) | MGLLMALT1PTGS2RPA1 | |
| SCHEMBL6986823 | 0.91 | MGLL (0.60) | MGLLMALT1ALDH1A1LMNAHPGD | |
| SCHEMBL6988238 | 0.85 | MGLL (0.51) | MGLLALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL6988584 | 0.79 | USP2 (0.43) | MGLLALDH1A1USP2LMNAPOLB | |
| SCHEMBL6986371 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBMAPK1KMT2ATSHR | |
| SCHEMBL6986113 | 0.77 | AGTR2 (0.41) | MGLLALDH1A1USP2LMNASMN1; SMN2 | |
| SCHEMBL6987355 | 0.76 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL6981026 | 0.75 | AGTR2 (0.40) | MGLLALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL6987526 | 0.75 | SIGMAR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |