Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090364 | 0.99 | MGLL (0.48) | MGLLMALT1ALDH1A1MEN1MAPT | |
| SCHEMBL6986823 | 0.92 | MGLL (0.60) | MGLLMALT1ALDH1A1PTGS2LMNA | |
| SCHEMBL6986647 | 0.92 | MGLL (0.50) | MGLLMALT1PTGS2RPA1 | |
| SCHEMBL6988238 | 0.86 | MGLL (0.51) | MGLLALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL6988584 | 0.80 | USP2 (0.43) | MGLLALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL6986371 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPK1KMT2ARPA1POLB | |
| SCHEMBL6986113 | 0.78 | AGTR2 (0.41) | MGLLALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6987355 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MEN1MAPTMAPK1KMT2A | |
| SCHEMBL6981026 | 0.76 | AGTR2 (0.40) | MGLLALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL6985626 | 0.75 | SLC5A1 (0.43) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |