Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751791 | 0.86 | SNCA (0.41) | SNCANOX1MEN1KMT2AMAPT | |
| SCHEMBL8470299 | 0.69 | SNCA (0.42) | SNCANOX1MEN1KMT2AMAPT | |
| SCHEMBL7107394 | 0.68 | POLB (0.36) | NOX1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5515460 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL224635 | 0.66 | ALOX5 (0.41) | GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL1443332 | 0.66 | CA2 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1247719 | 0.64 | GAA (0.43) | SNCANOX1MEN1KMT2AMAPT | |
| SCHEMBL4695235 | 0.64 | CA12 (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL293466 | 0.64 | PARP1 (0.57) | MEN1KMT2AALDH1A1HSD17B10GAA | |
| SCHEMBL29242101 | 0.63 | SNCA (0.63) | SNCANOX1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620809-B2 | Useful in treating or in preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-09-16 | — | — | US | disclosed |
| EP-1106608-B1 | Substituted (dihydro)benzoxazine and (dihydro)benzothiazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | LES LABORATOIRES SERVIER (FR) | 2001-06-14 | — | — | US | disclosed |
| EP-1106608-A1 | Substituted (dihydro)benzoxazine and (dihydro)benzothiazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | MTNR1A, MTNR1B, SQOR | SNCA 1146/4885NOX1 267/4885PSMB8 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.