Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987568 | 0.83 | BMPR1B (0.35) | NR3C2ADORA3ADORA1ADORA2ATP53 | |
| SCHEMBL6981881 | 0.80 | PDE10A (0.43) | NR3C2PDE10AMAPK14TP53 | |
| SCHEMBL6987158 | 0.80 | MEN1 (0.46) | — | |
| SCHEMBL6988129 | 0.79 | TSHR (0.40) | TP53 | |
| SCHEMBL6987522 | 0.79 | KMT2A (0.38) | — | |
| SCHEMBL6986889 | 0.75 | L3MBTL1 (0.40) | MGLL | |
| SCHEMBL6986812 | 0.69 | ALDH1A1 (0.40) | NPSR1 | |
| SCHEMBL7370829 | 0.68 | NR3C2 (0.44) | NR3C2MAPK14NPSR1TP53 | |
| SCHEMBL28147852 | 0.68 | ALDH1A1 (0.57) | NR3C2CACNA1B | |
| SCHEMBL6824757 | 0.67 | ADORA1 (0.38) | ADORA1MAPK14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |