Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 3/20 | 0.38 |
| ▸ | BAD | Q92934 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987522 | 0.85 | KMT2A (0.38) | KMT2AALDH1A1LMNARAB9AMAPT | |
| SCHEMBL6988129 | 0.82 | TSHR (0.40) | L3MBTL1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL6986823 | 0.77 | MGLL (0.60) | ALDH1A1LMNAKDM4ERAB9AMGLL | |
| SCHEMBL6981881 | 0.76 | PDE10A (0.43) | ALDH1A1LMNAHTTGAA | |
| SCHEMBL6987158 | 0.75 | MEN1 (0.46) | L3MBTL1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL6988697 | 0.75 | NR3C2 (0.43) | MGLL | |
| SCHEMBL6986647 | 0.69 | MGLL (0.50) | MGLL | |
| SCHEMBL6987595 | 0.69 | TDP1 (0.42) | L3MBTL1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL6988945 | 0.69 | MGLL (0.49) | BCL2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6984622 | 0.68 | AGTR2 (0.39) | KMT2AALDH1A1LMNAHRH3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |