Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003350 | 0.82 | VDR (0.47) | VDRCNR1NR3C1PGRNR3C2 | |
| SCHEMBL7003917 | 0.79 | KMT2A (0.54) | VDRKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL11050404 | 0.71 | MAOB (0.47) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11201464 | 0.67 | KMT2A (0.54) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2010410 | 0.67 | IDO1 (0.47) | KIF11KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL11193839 | 0.67 | ALDH1A1 (0.48) | MEN1ALDH1A1MAPTKMT2AMAOB | |
| Hydrochloric Acid SCHEMBL2013413 | 0.66 | IDO1 (0.49) | KIF11KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2592358 | 0.64 | ALDH1A1 (0.50) | ABCG2KIF11KDM4EMEN1ALDH1A1 | |
| SCHEMBL7372288 | 0.64 | CCNB2 (0.49) | VDRKIF11KDM4EMEN1ALDH1A1 | |
| SCHEMBL21399702 | 0.64 | NR3C1 (0.62) | VDRNR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341761-A1 | SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-$g(g) BINDING AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002030895-A1 | SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-η BINDING AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-18 | — | — | WO | disclosed |