Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004254 | 0.75 | DAO (0.46) | KDM4EBRD4MAPTTP53ALDH1A1 | |
| SCHEMBL20203369 | 0.72 | BRD9 (0.35) | KDM4ENQO2PTPN1BRD4ALDH1A1 | |
| SCHEMBL7005436 | 0.69 | MAPT (0.38) | PDE2APDE3BPDE3AKDM4EBRD4 | |
| SCHEMBL13833580 | 0.68 | GAA (0.57) | PTPN1BRD4MAPTTP53ALDH1A1 | |
| SCHEMBL22828053 | 0.66 | BRPF1 (0.32) | KDM4EBRD4MAPTALDH1A1 | |
| SCHEMBL256208 | 0.65 | ALDH1A1 (0.50) | KDM4ENQO2PTPN1ALKBH5FTO | |
| SCHEMBL7006877 | 0.65 | HTR3E (0.37) | KDM4EBRD4TP53ALDH1A1MEN1 | |
| SCHEMBL7006177 | 0.65 | DAO (0.36) | KDM4EBRD4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7006296 | 0.65 | TP53 (0.38) | BRD4MAPTTP53MEN1KMT2A | |
| SCHEMBL9279188 | 0.65 | ALOX5 (0.37) | SLC9A1KDM4ENQO2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |