Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628587 | 1.00 | ELANE (0.51) | ELANECAPN1CMA1MALT1 | |
| SCHEMBL29427202 | 0.88 | ELANE (0.49) | ELANECAPN1CMA1MALT1 | |
| SCHEMBL32682555 | 0.87 | ELANE (0.46) | ELANECAPN1CMA1 | |
| SCHEMBL7004057 | 0.86 | CMA1 (0.47) | ELANECMA1 | |
| SCHEMBL13814740 | 0.85 | ELANE (0.53) | ELANECAPN1CMA1MALT1 | |
| SCHEMBL7286279 | 0.80 | CAPN1 (0.51) | ELANECAPN1CMA1MALT1 | |
| SCHEMBL9744941 | 0.79 | ELANE (0.81) | ELANE | |
| SCHEMBL7289203 | 0.79 | ELANE (0.81) | ELANE | |
| SCHEMBL9745389 | 0.78 | ELANE (0.66) | ELANE | |
| SCHEMBL1506200 | 0.77 | ALDH1A1 (0.62) | ELANECAPN1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216324-A1 | Airway mucus secretion inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| US-20030212115-A1 | Remedies for inflammatory bowel diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-13 | — | — | US | claimed |
| EP-1323420-A1 | REMEDIES FOR INFLAMMATORY BOWEL DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-02 | — | — | EP | claimed |
| EP-1323419-A1 | AIRWAY MUCUS SECRETION INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-02 | — | — | EP | claimed |
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | ACCUTHERA, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | ACCUTHERA, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-20030216324-A1 | Airway mucus secretion inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| US-20030212115-A1 | Remedies for inflammatory bowel diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1323420-A1 | REMEDIES FOR INFLAMMATORY BOWEL DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| EP-1323419-A1 | AIRWAY MUCUS SECRETION INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212115-A1 | Remedies for inflammatory bowel diseases | NOS3, TPMT, NOS2 | ELANE 588/4885CAPN1 3534/4885CMA1 1941/4885 |
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | SCTR, CTRC, SERPINB1 | ELANE 4/4885CAPN1 470/4885CMA1 18/4885 |
| US-20030216324-A1 | Airway mucus secretion inhibitors | MUC1, CFTR, SERPINB1 | ELANE 19/4885CAPN1 1869/4885CMA1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.