Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL10935053 | 0.96 | — | — | |
| SCHEMBL8652975 | 0.79 | — | — | |
| SCHEMBL31322944 | 0.63 | — | — | |
| SCHEMBL31322905 | 0.63 | — | — | |
| SCHEMBL1752214 | 0.63 | — | — | |
| SCHEMBL11443061 | 0.61 | — | — | |
| SCHEMBL1751779 | 0.58 | — | — | |
| SCHEMBL1751937 | 0.58 | — | — | |
| SCHEMBL11327636 | 0.57 | — | — | |
| SCHEMBL15262149 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058115-B1 | Leukocyte classification reagent | NIHON KOHDEN CORP (JP) | 2003-05-02 | — | — | EP | disclosed |
| EP-1052509-B1 | Leukocyte classification reagent | NIHON KOHDEN CORP (JP) | 2003-05-02 | — | — | EP | disclosed |
| EP-1006361-B1 | Leukocyte classification reagent | NIHON KOHDEN CORP (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-0709674-B1 | Leukocyte classification reagent | NIHON KOHDEN CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-1058115-A2 | Leukocyte classification reagent | Nihon Kohden Corporation (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-1052509-A2 | Leukocyte classification reagent | Nihon Kohden Corporation (JP) | 2000-11-15 | — | — | EP | disclosed |
| EP-1006361-A2 | Leukocyte classification reagent | Nihon Kohden Corporation (JP) | 2000-06-07 | — | — | EP | disclosed |
| EP-0709674-A2 | Leukocyte classification reagent | Nihon Kohden Corporation (JP) | 1996-05-01 | — | — | EP | disclosed |