SCHEMBL2646288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2308236	0.84	PSIP1 (0.58)	ALDH1A1CYP3A4CYP2C9CYP2C19SIGMAR1
	SCHEMBL92881	0.80	ALDH1A1 (0.72)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2
	SCHEMBL1368829	0.78	KMT2A (0.51)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2
	SCHEMBL1368369	0.78	L3MBTL1 (0.53)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2
	SCHEMBL2646220	0.78	CA2 (0.53)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2
	SCHEMBL10619867	0.78	ALDH1A1 (0.47)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2
	SCHEMBL2148722	0.78	GAA (0.69)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2
	SCHEMBL198253	0.78	PLCG1 (0.61)	ALDH1A1CYP3A4CYP2C9CYP2C19SIGMAR1
	SCHEMBL7029959	0.78	CA2 (0.42)	ALDH1A1CYP3A4CYP2C9CYP2C19SIGMAR1
	SCHEMBL7033001	0.78	CA2 (0.64)	ALDH1A1CYP3A4CYP2C9CYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.