Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.50 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.49 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.47 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.47 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264266 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7033984 | 0.88 | TDP1 (0.97) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2384122 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL925266 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL133646 | 0.87 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL133647 | 0.87 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29359461 | 0.87 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| Olsalazine SCHEMBL3476110 | 0.86 | MEN1 (0.66) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| Olsalazine SCHEMBL29454399 | 0.86 | MEN1 (0.66) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| Olsalazine SCHEMBL29767 | 0.86 | MEN1 (0.66) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029954-B2 | Liquid fertilizer composition containing color change indicator | THE ANDERSONS, INC. (US) | 2018-07-24 | — | — | US | claimed |
| US-20150344380-A1 | LIQUID FERTILIZER COMPOSITION CONTAINING COLOR CHANGE INDICATOR | THE ANDERSONS, INC. | 2015-12-03 | — | — | US | claimed |
| US-10029954-B2 | Liquid fertilizer composition containing color change indicator | THE ANDERSONS, INC. (US) | 2018-07-24 | — | — | US | disclosed |
| US-20150344380-A1 | LIQUID FERTILIZER COMPOSITION CONTAINING COLOR CHANGE INDICATOR | THE ANDERSONS, INC. | 2015-12-03 | — | — | US | disclosed |
| US-20030220213-A1 | A formulation containg a color indicator to indicate a color change when the finish is completely removed; preferably the floor finish is acidic, the floor finish remover is alkaline and the color indicator is pH sensitive; phthalein dyes | JOHNSONDIVERSEY, INC. | 2003-11-27 | — | — | US | disclosed |