SCHEMBL7036346

SCHEMBL7036346

NC(CCc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 4/20 0.53
GRIK2 Q13002 2/20 0.53
GRIK3 Q13003 2/20 0.53
GRIA1 P42261 1/20 0.53
GRIA2 P42262 1/20 0.53
GRIA3 P42263 1/20 0.53
GRIA4 P48058 1/20 0.53
PPARG P37231 3/20 0.50
PPARA Q07869 3/20 0.50
SLC1A5 Q15758 2/20 0.50
KIF11 P52732 3/20 0.48
SLC7A5 Q01650 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15389814 1.00 GRIK1 (0.53) GRIK1GRIK2GRIK3GRIA1GRIA2
SCHEMBL15389812 1.00 GRIK1 (0.53) GRIK1GRIK2GRIK3GRIA1GRIA2
SCHEMBL5079189 0.89 PPARA (0.59) GRIK1PPARGPPARASLC1A5KIF11
SCHEMBL5079192 0.89 PPARA (0.59) GRIK1PPARGPPARASLC1A5KIF11
SCHEMBL10420699 0.86 PPARA (0.52) GRIK1PPARGPPARASLC1A5KIF11
SCHEMBL10419212 0.86 PPARA (0.52) GRIK1PPARGPPARASLC1A5KIF11
SCHEMBL27255434 0.84 BHMT (0.49) PPARGPPARAKIF11
SCHEMBL25356342 0.83 GRIK1 (0.54) GRIK1GRIK2GRIK3GRIA1GRIA2
SCHEMBL1768639 0.83 SLC7A5 (0.67) GRIK1GRIK2GRIK3GRIA1GRIA2
SCHEMBL9394667 0.83 SLC7A5 (0.67) GRIK1GRIK2GRIK3GRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US claimed
WO-2024148312-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-11 WO claimed
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 EP disclosed
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR UNIV CALIFORNIA (US) 2026-03-26 US disclosed
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-02 US disclosed
CN-112672747-B Peptides for activating cell signaling in osteoprogenitor cells 加利福尼亚大学董事会 2025-02-18 CN disclosed
WO-2024263637-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-26 WO disclosed
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-03 US disclosed
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
WO-2024148312-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-11 WO disclosed
US-20210147475-A1 METHOD FOR PRODUCING CYCLIC ORGANIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-05-20 US disclosed
US-20200131669-A1 CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2020-04-30 US disclosed
EP-3636807-A1 CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME Chugai Seiyaku Kabushiki Kaisha (JP) 2020-04-15 EP disclosed
CN-110869544-A Cyclic peptide compound having high membrane permeability and library containing same 中外制药株式会社 2020-03-06 CN disclosed
WO-2017060488-A1 NEW TRPA1 ANTAGONISTS ALMIRALL, S.A. (ES) 2017-04-13 WO disclosed
EP-0822827-B1 ANTAGONISTS OF LHRH UNIV TEXAS (US) 2003-03-05 EP disclosed
EP-0822827-A4 ANTAGONISTS OF LHRH UNIV TEXAS (US) 2001-07-11 EP disclosed
EP-0822827-A1 ANTAGONISTS OF LHRH BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1998-02-11 EP disclosed
WO-1996033729-A1 ANTAGONISTS OF LHRH BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1996-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR GRIK1 1212/4885GRIK2 848/4885GRIK3 775/4885
US-20200131669-A1 CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME VIP, SLC7A1, TRPV1 GRIK1 2079/4885GRIK2 1986/4885GRIK3 2027/4885
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair PDGFA, PDGFRB, TEK GRIK1 4649/4885GRIK2 4772/4885GRIK3 4522/4885
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR PDGFA, DCLRE1A, PDGFRA GRIK1 4089/4885GRIK2 4198/4885GRIK3 4465/4885
US-20210147475-A1 METHOD FOR PRODUCING CYCLIC ORGANIC COMPOUND SCTR, CTRC, DCXR GRIK1 4686/4885GRIK2 4629/4885GRIK3 4440/4885
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells ITGB4, ITGA4, ITGB1 GRIK1 1782/4885GRIK2 2679/4885GRIK3 2004/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR GRIK1 1212/4885GRIK2 848/4885GRIK3 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.