SCHEMBL705237

SCHEMBL705237

CCO[SiH2]CCC(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 8/20 0.42
HTR2A P28223 8/20 0.42
SIGMAR1 Q99720 1/20 0.42
CYP3A4 P08684 2/20 0.39
LMNA P02545 2/20 0.39
HTR1A P08908 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
ADRA1A P35348 2/20 0.39
OPRM1 P35372 2/20 0.39
DRD3 P35462 2/20 0.39
SLC6A3 Q01959 2/20 0.39
KCNH2 Q12809 2/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
CHRM1 P11229 1/20 0.39
SMPD1 P17405 1/20 0.39
DRD1 P21728 1/20 0.39
TBXA2R P21731 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702334 0.85 HRH1 (0.40) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL702750 0.82 SIGMAR1 (0.41) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL705040 0.80 HRH1 (0.45) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL708761 0.80 HTR2A (0.39) HRH1HTR2ASIGMAR1LMNAALOX15
SCHEMBL3481513 0.78 HRH1 (0.40) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL703036 0.77 CYP3A4 (0.43) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL704049 0.76 HRH1 (0.45) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL713409 0.76 HRH1 (0.41) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL3481390 0.75 SIGMAR1 (0.41) HRH1HTR2ASIGMAR1CYP3A4LMNA
SCHEMBL705340 0.74 HRH1 (0.43) HRH1HTR2ASIGMAR1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
US-5439746-A Formed by coating or impregnating a reinforcement sheet and curing; mechanical strength; corrosion and heat resistance; electrical properties KABUSHIKI KAISHA TOSHIBA (JP) 1995-08-08 US disclosed