Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 16/20 | 0.45 |
| ▸ | TUBB | P07437 | 16/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 16/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 16/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 16/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 16/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 16/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 16/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 16/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 16/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 16/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 16/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 16/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 16/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 16/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065226 | 0.89 | FBP1 (0.42) | KDM4EGAAHPGD | |
| SCHEMBL7063837 | 0.86 | HTR6 (0.43) | GAA | |
| SCHEMBL7067545 | 0.85 | HTR6 (0.40) | KDM4EGAAHPGD | |
| SCHEMBL7066081 | 0.85 | KAT6A (0.48) | — | |
| SCHEMBL7060983 | 0.82 | HSD11B1 (0.48) | HPGD | |
| SCHEMBL7062024 | 0.82 | ALDH1A1 (0.44) | KDM4EGAA | |
| SCHEMBL10003711 | 0.76 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5716657 | 0.74 | MEN1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10002790 | 0.69 | RAB9A (0.41) | HPGD | |
| SCHEMBL7065124 | 0.67 | MEN1 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158216-A1 | 2-acyl indole derivatives and their use as antitumor agents | BAXTER ONCOLOGY GMBH | 2003-08-21 | — | — | US | disclosed |
| US-20020091124-A1 | 2-acyl indole derivatives and their use as antitumor agents | BECKERS THOMAS (DE) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158216-A1 | 2-acyl indole derivatives and their use as antitumor agents | IDO1, IDO2, INMT | TUBB4A 240/4885TUBB 183/4885TUBA3C 259/4885 |
| US-20020091124-A1 | 2-acyl indole derivatives and their use as antitumor agents | IDO1, IDO2, INMT | TUBB4A 240/4885TUBB 183/4885TUBA3C 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.