Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 10/20 | 0.39 |
| ▸ | RARG | P13631 | 9/20 | 0.39 |
| ▸ | RARA | P10276 | 8/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011496 | 0.77 | KDM4E (0.41) | RXRAPOLBRXRBCYP26A1CYP26B1 | |
| SCHEMBL304686 | 0.73 | CA1 (0.38) | RXRAPOLBRXRBRXRGCA12 | |
| SCHEMBL6539867 | 0.73 | AR (0.38) | POLBARLMNATP53 | |
| SCHEMBL5460910 | 0.72 | AR (0.47) | AR | |
| SCHEMBL4618799 | 0.72 | NNMT (0.38) | RXRARXRBRARBRARGRARA | |
| Bromide SCHEMBL6028566 | 0.71 | PGR (0.41) | SMN1; SMN2ARALDH1A1KDM4ETHRB | |
| SCHEMBL17285619 | 0.70 | POLB (0.47) | SMN1; SMN2POLBCA12CA2CA4 | |
| SCHEMBL11371183 | 0.70 | ALDH1A1 (0.44) | SMN1; SMN2POLBARALDH1A1KDM4E | |
| SCHEMBL27780572 | 0.70 | RARB (0.41) | RXRASMN1; SMN2POLBRXRBRARB | |
| SCHEMBL7092850 | 0.70 | SNCA (0.43) | SMN1; SMN2POLBCA12CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387631-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
| US-8398722-B2 | Phenylpyrido [1,2-A] indolium-derived thiol/disulfide dye, dye composition comprising this dye, process for lightening keratin materials using this dye | L'OREAL (FR) | 2013-03-19 | — | — | US | disclosed |
| US-20120266392-A1 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| WO-2009037324-A2 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |
| US-20030211454-A1 | Detection reagent | GE HEALTHCARE UK LIMITED (GB) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387631-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | CD68, MSR1, CD47 | RXRA 216/4885SMN1; SMN2 3271/4885POLB 3422/4885 |
| US-20030211454-A1 | Detection reagent | DDT, DLD, DLK1 | RXRA 2813/4885SMN1; SMN2 4569/4885POLB 1817/4885 |
| US-20120266392-A1 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | KRT18, IK, PTMA | RXRA 3264/4885SMN1; SMN2 4854/4885POLB 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.