SCHEMBL707570

SCHEMBL707570

CO[Si](OC)(OC)c1ccc(COC(=O)C=[N+]=[N-])cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 4/20 0.36
HCAR2 Q8TDS4 1/20 0.36
LMNA P02545 1/20 0.34
TGM2 P21980 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CA12 O43570 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
CA5A P35218 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
AKR1B10 O60218 1/20 0.32
AKR1B1 P15121 1/20 0.32
F13A1 P00488 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19371290 0.77 ALDH1A1 (0.56) CYP1A2CYP2C19POLBALDH1A1MEN1
SCHEMBL43967 0.77 HCAR2 (0.59) HCAR2LMNATGM2CYP1A2CYP2C9
SCHEMBL43607 0.75 HCAR2 (0.38) METHCAR2LMNATGM2CYP1A2
SCHEMBL43819 0.74 GABRA1 (0.33) METHCAR2LMNATGM2CYP1A2
SCHEMBL43077 0.74 GAA (0.44) HCAR2ALDH1A1NPC1GAATSHR
SCHEMBL9784740 0.72 RAB9A (0.49) POLBALDH1A1SMN1; SMN2
SCHEMBL8509226 0.70 CYP17A1 (0.48) LMNACYP1A2CYP2C9ALDH1A1MEN1
SCHEMBL4420825 0.69 LTA4H (0.39) CA12CA4CA6CA5ACA7
SCHEMBL19389577 0.69 AGXT (0.34) LMNA
SCHEMBL1027911 0.68 IDO1 (0.40) LMNAPOLBALDH1A1NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738748-B1 Process for treating a stainless steel article to improve its adhesion to a rubber composition MICHELIN & CIE (FR) 2005-08-17 EP claimed
US-5989712-A Process for treating a body of stainless steel so as to promote its adherence to a rubber composition MICHELIN RECHERCHE ET TECHNIQUE SA (FR) 1999-11-23 US claimed
US-5958161-A RUBBER, STEEL COMPOSITE; ACTIVATION, APPLYING AN ORGANOSILICON COMPOUND MICHELIN & CIE (FR) 1999-09-28 US claimed
US-5789080-A TIRES, SILANE COUPLER COMPAGNIE GENERALE DES ESTABLISSEMENTS (FR) 1998-08-04 US claimed
EP-2615149-B1 JOINT AND METHOD FOR MANUFACTURING SUCH A JOINT BIWI SA (CH) 2015-09-02 EP disclosed
EP-2615149-A1 Joint and method for manufacturing such a joint BIWI S.A. (CH) 2013-07-17 EP disclosed
EP-2363036-B1 Method for producing a part comprising an elastomer covering, and part obtained by this method BIWI SA (CH) 2012-11-07 EP disclosed
EP-2469359-A1 Joint and method for manufacturing such a joint BIWI S.A. (CH) 2012-06-27 EP disclosed
EP-2423763-A2 Method for manufacturing a timepiece comprising an elastomer covering and piece thus obtained BIWI S.A. (CH) 2012-02-29 EP disclosed
EP-2363036-A1 Method for producing a part comprising an elastomer covering, and part obtained by this method BIWI S.A. (CH) 2011-09-07 EP disclosed
EP-0738748-B1 Process for treating a stainless steel article to improve its adhesion to a rubber composition MICHELIN & CIE (FR) 2005-08-17 EP disclosed
US-5989712-A Process for treating a body of stainless steel so as to promote its adherence to a rubber composition MICHELIN RECHERCHE ET TECHNIQUE SA (FR) 1999-11-23 US disclosed
US-5958161-A RUBBER, STEEL COMPOSITE; ACTIVATION, APPLYING AN ORGANOSILICON COMPOUND MICHELIN & CIE (FR) 1999-09-28 US disclosed
US-5789080-A TIRES, SILANE COUPLER COMPAGNIE GENERALE DES ESTABLISSEMENTS (FR) 1998-08-04 US disclosed
EP-0738748-A1 Process for treating a stainless steel article to improve its adhesion to a rubber composition COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN-MICHELIN & CIE (FR) 1996-10-23 EP disclosed
EP-0119011-A1 Adhesive process HERCULES INCORPORATED (US) 1984-09-19 EP disclosed
US-4447495-A AN AZIDOSILANE COUPLING AGENT FOR ADHEARING POLYMER AND SILICEOUS MATERIAL HERCULES, INCORPORATED (US) 1984-05-08 US disclosed