Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077874 | 0.88 | F2 (0.46) | MAOAMAOBCYP19A1PRMT1F10 | |
| SCHEMBL10279296 | 0.82 | CA12 (0.40) | GABBR2GABBR1F10MMP2MMP9 | |
| SCHEMBL7073687 | 0.81 | GABRP (0.43) | GABBR2GABBR1F10MMP2MMP9 | |
| SCHEMBL7080823 | 0.79 | GABBR2 (0.49) | GABBR2GABBR1PRMT1MMP2ALDH1A1 | |
| SCHEMBL7080988 | 0.79 | ITGB3 (0.44) | CA1CA2CA9ALDH1A1ATM | |
| SCHEMBL8909238 | 0.78 | GABBR2 (0.56) | GABBR2GABBR1MMP2ALDH1A1ATM | |
| SCHEMBL7130131 | 0.78 | ITGB3 (0.46) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7133113 | 0.77 | MEN1 (0.47) | GABBR2GABBR1PRMT1MMP2MMP9 | |
| SCHEMBL7080966 | 0.77 | KDR (0.47) | ALDH1A1ATM | |
| SCHEMBL7073753 | 0.76 | GABBR2 (0.50) | GABBR2GABBR1MMP2CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |