Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790563 | 0.74 | TRPA1 (0.43) | IDO1GAAMAPTSMN1; SMN2SLC6A4 | |
| SCHEMBL31453567 | 0.73 | IDO1 (0.51) | IDO1MAPTTSHRSLC6A4HTR2A | |
| SCHEMBL24258323 | 0.71 | KMT2A (0.47) | MAPTSMN1; SMN2KCNH2CYP3A4ALDH1A1 | |
| SCHEMBL7080583 | 0.70 | TSHR (0.40) | IDO1TSHRSMN1; SMN2SLC6A4HTR2A | |
| SCHEMBL91286 | 0.70 | POLB (0.40) | GAATSHRSMN1; SMN2SLC6A4HTR2A | |
| SCHEMBL5847395 | 0.70 | CSNK2A1 (0.57) | IDO1L3MBTL1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5847393 | 0.70 | L3MBTL1 (0.39) | IDO1TSHRSMN1; SMN2SLC6A4HTR2A | |
| SCHEMBL13179975 | 0.70 | L3MBTL1 (0.39) | IDO1GAATSHRSMN1; SMN2SLC6A4 | |
| SCHEMBL3759408 | 0.70 | L3MBTL1 (0.39) | IDO1TSHRSMN1; SMN2SLC6A4HTR2A | |
| SCHEMBL14368008 | 0.68 | RORC (0.58) | MAPTSMN1; SMN2L3MBTL1CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236257-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the cogulation cascade | PHARMACIA CORPORATION | 2003-12-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236257-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the cogulation cascade | PLG, TFPI, PLAT | IDO1 1099/4885GAA 489/4885MAPT 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.