SCHEMBL7080646

SCHEMBL7080646

CCCC(=O)NS(=O)(=O)c1ccccc1N(Oc1ccoc1)C(=O)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ITGAV P06756 2/20 0.33
TDP2 O95551 1/20 0.33
PAX8 Q06710 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
TLR9 Q9NR96 1/20 0.33
ITGA2 P17301 1/20 0.33
LTA4H P09960 1/20 0.32
AGTR1 P30556 2/20 0.32
AGTR2 P50052 2/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
LIMK1 P53667 2/20 0.31
CCR8 P51685 1/20 0.31
F2R P25116 1/20 0.31
LIMK2 P53671 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7081572 0.85 CETP (0.33) ITGAVITGA2LTA4HAGTR1AGTR2
SCHEMBL7076731 0.83 RAPGEF3 (0.43) LTA4H
SCHEMBL7083371 0.82 AGTR1 (0.33) TDP2PAX8HKDC1TLR9LTA4H
SCHEMBL7080257 0.82 PTGS2 (0.38)
SCHEMBL7083342 0.75 RAPGEF3 (0.37) LTA4HAGTR1AGTR2
SCHEMBL7077441 0.73 AGTR1 (0.33) LTA4HAGTR1AGTR2ALOX5
SCHEMBL7080333 0.72 GRM2 (0.41)
SCHEMBL7744231 0.67 CASP1 (0.51)
SCHEMBL7048489 0.64 POLB (0.43) AGTR1AGTR2
SCHEMBL29165186 0.64 CA9 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162818-A1 Acylsulfonamide derivative AJINOMOTO CO. INC. (JP) 2003-08-28 US disclosed
US-6555584-B1 Acetyl-coa carboxylase inhibitors AJINOMOTO CO., INC. (JP) 2003-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162818-A1 Acylsulfonamide derivative ACSS2, ACACA, FASN ITGAV 4796/4885TDP2 4739/4885PAX8 4767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.