SCHEMBL7077441

SCHEMBL7077441

CCCC(=O)NS(=O)(=O)c1ccccc1N(OCc1ccsc1)C(=O)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.33
AGTR2 P50052 2/20 0.33
PTGER4 P35408 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALOX5 P09917 1/20 0.32
LTA4H P09960 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083371 0.85 AGTR1 (0.33) AGTR1AGTR2LTA4H
SCHEMBL7083342 0.83 RAPGEF3 (0.37) AGTR1AGTR2LTA4H
SCHEMBL7081572 0.83 CETP (0.33) AGTR1AGTR2L3MBTL1CYP3A4CYP2C19
SCHEMBL7080333 0.82 GRM2 (0.41) CYP3A4TDP1
SCHEMBL7076731 0.74 RAPGEF3 (0.43) LTA4HTDP1
SCHEMBL7080646 0.73 ITGAV (0.33) AGTR1AGTR2ALOX5LTA4H
SCHEMBL7080257 0.72 PTGS2 (0.38) CYP3A4
SCHEMBL7744231 0.63 CASP1 (0.51) L3MBTL1
SCHEMBL7083369 0.63 RAB9A (0.43) L3MBTL1TDP1
SCHEMBL7048489 0.63 POLB (0.43) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162818-A1 Acylsulfonamide derivative AJINOMOTO CO. INC. (JP) 2003-08-28 US disclosed
US-6555584-B1 Acetyl-coa carboxylase inhibitors AJINOMOTO CO., INC. (JP) 2003-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162818-A1 Acylsulfonamide derivative ACSS2, ACACA, FASN AGTR1 845/4885AGTR2 983/4885PTGER4 2942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.