Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973129 | 0.92 | ALDH1A1 (0.35) | KDM4EALDH1A1HDAC1HDAC8L3MBTL1 | |
| SCHEMBL6974469 | 0.92 | TLR7 (0.36) | KDM4EALDH1A1HDAC1HDAC8L3MBTL1 | |
| SCHEMBL6969306 | 0.91 | KMT2A (0.39) | KDM4EALDH1A1L3MBTL1S1PR3KMT2A | |
| SCHEMBL7086211 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2ASMN1; SMN2GABRA1GABRA5 | |
| SCHEMBL6972580 | 0.90 | GRIN1 (0.36) | HDAC1HDAC8S1PR3KMT2AENPP2 | |
| SCHEMBL8342977 | 0.87 | LMNA (0.45) | HDAC1HDAC8ENPP2PTGDR2 | |
| SCHEMBL6971258 | 0.87 | LMNA (0.40) | HDAC1HDAC8L3MBTL1TLR7S1PR3 | |
| SCHEMBL7081149 | 0.86 | TLR7 (0.39) | KDM4EALDH1A1HDAC1HDAC8TLR7 | |
| SCHEMBL6973586 | 0.85 | CYP11B1 (0.41) | KDM4EHDAC1HDAC8KMT2AHTT | |
| SCHEMBL7086385 | 0.84 | TLR7 (0.35) | KDM4EALDH1A1L3MBTL1TLR7S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |