Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.37 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974903 | 0.89 | TP53 (0.39) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL6983505 | 0.85 | NR3C1 (0.42) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL6985322 | 0.85 | GAA (0.41) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL7085527 | 0.85 | NR3C1 (0.51) | MAPTTP53LMNAPKMKMT2A | |
| SCHEMBL6984759 | 0.80 | LMNA (0.47) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL6985749 | 0.80 | ALDH1A1 (0.48) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL6982764 | 0.80 | FPR1 (0.43) | MAPTLMNAPKMKMT2AMEN1 | |
| SCHEMBL7408050 | 0.80 | TP53 (0.40) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL6976883 | 0.80 | NR3C1 (0.38) | MAPTTP53LMNATHRBPKM | |
| SCHEMBL6982163 | 0.79 | SLC16A3 (0.45) | MAPTTP53LMNATHRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |