SCHEMBL7090673

SCHEMBL7090673

Nc1c(F)cc(Cl)c2nc(C3CC3)oc12

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.35
ACHE P22303 5/20 0.33
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6678092 0.72 LMNA (0.33) RAB9A
SCHEMBL7249054 0.70 GRM4 (0.30)
SCHEMBL7086455 0.69 GABRA2 (0.30)
SCHEMBL28318365 0.64 HTR3A (0.43) ADORA3ACHENPC1ALDH1A1RAB9A
SCHEMBL3822914 0.62 CA1 (0.43) ALDH1A1
SCHEMBL14758308 0.62 ADORA3 (0.34) ADORA3NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL9148367 0.62 SMN1; SMN2 (0.38) PIM3ALDH1A1SMN1; SMN2
SCHEMBL3296078 0.61 ACHE (0.33) ACHE
SCHEMBL26579791 0.61 TTR (0.39) NPC1
SCHEMBL6794232 0.61 FBP1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216257-A1 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216257-A1 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides CYP1B1, DDT, CYP1A1 ADORA3 2236/4885ACHE 343/4885PIM1 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.