Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.65 |
| ▸ | FEN1 | P39748 | 4/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085381 | 0.87 | AHR (0.65) | AHRFEN1ALOX5APGPR84CA1 | |
| SCHEMBL10094662 | 0.81 | AHR (0.61) | AHRFEN1ALOX5APNPC1GUSB | |
| SCHEMBL856313 | 0.80 | AHR (0.70) | AHRNPC1GUSBGPR84MAP3K11 | |
| SCHEMBL18805065 | 0.80 | AHR (1.00) | AHRNPC1GUSBGPR84CA12 | |
| SCHEMBL228554 | 0.80 | AHR (1.00) | AHRNPC1GUSBGPR84CA12 | |
| SCHEMBL30915425 | 0.78 | PARP10 (0.46) | AHRFEN1ALOX5APGUSBPARP10 | |
| Methane SCHEMBL27929619 | 0.78 | AHR (0.95) | AHRNPC1GUSBGPR84CA12 | |
| SCHEMBL10094402 | 0.77 | AHR (0.56) | AHRFEN1ALOX5APNPC1GUSB | |
| SCHEMBL4286388 | 0.76 | MGLL (0.48) | CA12CA1CA2CA9PIM1 | |
| SCHEMBL5850255 | 0.75 | NPC1 (0.79) | AHRNPC1GUSBMAP3K11CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021303-A1 | BKCA CHANNEL ACTIVATOR FOR TREATING MUSCULAR DISORDER | CANBEX THERAPEUTICS LTD (GB) | 2018-01-25 | — | — | US | disclosed |
| US-20180021303-A1 | BKCA CHANNEL ACTIVATOR FOR TREATING MUSCULAR DISORDER | CANBEX THERAPEUTICS LTD (GB) | 2018-01-25 | — | — | US | disclosed |
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021303-A1 | BKCA CHANNEL ACTIVATOR FOR TREATING MUSCULAR DISORDER | KCNMA1, KCNMB1, KCNA1 | AHR 4507/4885FEN1 4593/4885ALOX5AP 3080/4885 |
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | AHR 379/4885FEN1 4100/4885ALOX5AP 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.