Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.41 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283040 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL7207850 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL7098262 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL626430 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL7096164 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL223461 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL7098222 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL9651092 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL7100030 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 | |
| SCHEMBL472819 | 1.00 | CA2 (0.41) | CA2CA1CYP3A4TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964036-B1 | Water-based ball-point pen ink composition | PILOT INK CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0964036-A2 | Water-based ball-point pen ink composition | THE PILOT INK CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0672620-B1 | Process for reducing the moisture content of alumina trihydrate | CYTEC TECH CORP (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0672620-A1 | Process for reducing the moisture content of alumina trihydrate | CYTEC TECHNOLOGY CORP. (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5451329-A | Sulfosuccinate and oil | CYTEC TECHNOLOGY CORP. (US) | 1995-09-19 | — | — | US | disclosed |
| US-4022731-A | ACRYLAMIDE, OIL, EMULSIFYING AGENT | AMERICAN CYANAMID COMPANY (US) | 1977-05-10 | — | — | US | disclosed |