Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096448 | 0.77 | GSK3A (0.32) | KDM4E | |
| SCHEMBL8575326 | 0.61 | TSHR (0.49) | P2RX7TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5205624 | 0.60 | NPC1 (0.69) | MEN1KMT2AENPP3ENPP1ENPP2 | |
| SCHEMBL8577964 | 0.59 | KDM4E (0.43) | P2RX7TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL3188745 | 0.59 | ENPP3 (0.69) | MEN1KMT2AENPP3ENPP1ENPP2 | |
| SCHEMBL5523975 | 0.58 | ALDH1A1 (0.75) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27793138 | 0.58 | ALDH1A1 (0.61) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14993138 | 0.57 | EPHX2 (0.55) | ALDH1A1SMN1; SMN2CYP1A2NPC1RAB9A | |
| SCHEMBL8587581 | 0.57 | ALDH1A1 (0.63) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18875023 | 0.57 | RAB9A (0.58) | MEN1KMT2AALDH1A1ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087973-B1 | IMIDAZOTRIAZOLOPYRIMIDINES USED AS A DRUG HAVING AN ADENOSINE ANTAGONIST ACTIVITY | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-01-08 | — | — | EP | disclosed |