SCHEMBL7097950

SCHEMBL7097950

N#CC(F)c1cc(Cl)cc(C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
RAPGEF3 O95398 7/20 0.36
RAPGEF4 Q8WZA2 5/20 0.36
ALDH1A1 P00352 1/20 0.34
PKM P14618 1/20 0.34
SHMT1 P34896 1/20 0.34
AHR P35869 1/20 0.33
NOTUM Q6P988 1/20 0.32
KIF11 P52732 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
DDR1 Q08345 2/20 0.31
SLC13A3 Q8WWT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10913469 0.75 RAPGEF4 (0.39) GAAL3MBTL1RAPGEF4ALDH1A1AHR
SCHEMBL1008766 0.74 RAPGEF3 (0.40) GAAL3MBTL1RAPGEF3RAPGEF4ALDH1A1
SCHEMBL628010 0.73 KIF11 (0.44) RAPGEF3RAPGEF4AHRKIF11DDR1
SCHEMBL9967739 0.73 RAPGEF4 (0.41) L3MBTL1RAPGEF4ALDH1A1AHRNOTUM
SCHEMBL5188795 0.73 PNMT (0.49) GAA
SCHEMBL28944233 0.72 SLC13A3 (0.38) AHRDDR1SLC13A3
Nitrogen SCHEMBL9592328 0.71 AHR (0.48) GAAL3MBTL1RAPGEF4ALDH1A1AHR
SCHEMBL195126 0.71 KIF11 (0.45) L3MBTL1ALDH1A1PKMKIF11
SCHEMBL321756 0.71 AHR (0.52) GAAL3MBTL1RAPGEF4ALDH1A1AHR
SCHEMBL3786224 0.71 RAPGEF4 (0.47) RAPGEF4ALDH1A1AHRNOTUMSLC13A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528657-B2 For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-04 US disclosed
US-20030023099-A1 Novel fluorescent carbazole derivative HIROSE ENGINEERING CO., LTD. (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030023099-A1 Novel fluorescent carbazole derivative CBR3, AANAT, SIRT3 GAA 3940/4885L3MBTL1 1222/4885RAPGEF3 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.