Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098655 | 0.84 | RECQL (0.46) | RECQLCTSKALDH1A1LMNAPRKCA | |
| SCHEMBL3420398 | 0.81 | RECQL (0.39) | RECQLALDH1A1LMNAPRKCAMEN1 | |
| SCHEMBL5155378 | 0.80 | FAAH (0.37) | RECQL | |
| SCHEMBL10340318 | 0.80 | RECQL (0.52) | RECQLCTSKALDH1A1LMNAPRKCA | |
| SCHEMBL9839591 | 0.79 | RECQL (0.51) | RECQLCTSKALDH1A1LMNAPRKCA | |
| SCHEMBL2727544 | 0.77 | GPR84 (0.39) | MEN1CYP2C19KMT2A | |
| SCHEMBL22711556 | 0.77 | CA2 (0.42) | ALDH1A1LMNAMEN1CYP2C19KMT2A | |
| Potassium Ion SCHEMBL11053761 | 0.76 | GPR84 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL354781 | 0.75 | FAAH (0.44) | RECQLALDH1A1LMNA | |
| SCHEMBL11416511 | 0.74 | RECQL (0.49) | RECQLALDH1A1LMNAPRKCAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964036-B1 | Water-based ball-point pen ink composition | PILOT INK CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |