Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354781 | 0.91 | FAAH (0.44) | FAAHRECQLCNR1CNR2CYP3A4 | |
| SCHEMBL1092383 | 0.89 | FAAH (0.52) | FAAHRECQLCNR1CNR2 | |
| SCHEMBL6128388 | 0.86 | RECQL (0.46) | FAAHRECQLCNR1CNR2CYP3A4 | |
| SCHEMBL4385317 | 0.84 | CYP19A1 (0.36) | — | |
| SCHEMBL5155385 | 0.84 | RECQL (0.44) | FAAHRECQLCNR1CNR2 | |
| Potassium Ion SCHEMBL7098657 | 0.80 | RECQL (0.35) | RECQL | |
| SCHEMBL8526920 | 0.79 | LMNA (0.34) | TSHR | |
| SCHEMBL8408859 | 0.77 | RECQL (0.54) | FAAHRECQLCNR1CNR2CYP3A4 | |
| SCHEMBL20773925 | 0.76 | RECQL (0.52) | FAAHRECQLCNR1CNR2CYP3A4 | |
| SCHEMBL6121600 | 0.76 | FAAH (0.50) | FAAHRECQLCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660696-B2 | LIPSTICKS | PROCTER & GAMBLE (US) | 2007-01-10 | — | — | EP | disclosed |
| EP-0950392-B1 | Non-sweating lipsticks | PROCTER & GAMBLE (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20020058051-A1 | SKIN CARE COMPOSITIONS | NAWAZ ZAHID (GB) | 2002-05-16 | — | — | US | disclosed |
| EP-0906077-A4 | SKIN CARE COMPOSITIONS | PROCTER & GAMBLE (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6325995-B1 | Lipsticks compositions containing association structures | THE PROCTER & GAMBLE COMPANY | 2001-12-04 | — | — | US | disclosed |
| EP-0884996-A4 | SKIN CARE COMPOSITIONS | PROCTER & GAMBLE (US) | 2001-05-30 | — | — | EP | disclosed |
| EP-0725620-B1 | NON-SWEATING LIPSTICKS | PROCTER & GAMBLE (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-1051149-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0778765-A4 | COSMETIC MAKE-UP COMPOSITIONS | PROCTER & GAMBLE (US) | 2000-04-19 | — | — | EP | disclosed |
| US-6013269-A | OIL-IN-WATER EMULSION COMPRISING VOLATILE SILICONE OIL AND/OR VOLATILE HYDROCARBON OIL, NON-VOLATILE OIL, PIGMENT AND ORGANIC AMPHIPHILIC MATERIAL CAPABLE OF FORMING SMECTIC LYOTROPIC LIQUID CRYSTALS IN PRODUCT OR ON THE SKIN | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-5688831-A | LIQUID CRYSTALS | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1997032561-A1 | SKIN CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |
| WO-1997032560-A1 | SKIN CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |
| EP-0778765-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0660696-B1 | LIPSTICKS | PROCTER & GAMBLE (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0725620-A1 | NON-SWEATING LIPSTICKS | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1996011665-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |
| EP-0706365-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995011000-A1 | NON-SWEATING LIPSTICKS | THE PROCTER & GAMBLE COMPANY (US) | 1995-04-27 | — | — | WO | disclosed |
| WO-1994028860-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058051-A1 | SKIN CARE COMPOSITIONS | CUTA, KRT18, POLR1C | FAAH 3551/4885RECQL 1023/4885CNR1 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.