Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108605 | 0.77 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL7103681 | 0.77 | LMNA (0.35) | PTGS2 | |
| SCHEMBL7018582 | 0.77 | HCRTR2 (0.36) | PTGS2 | |
| SCHEMBL7019518 | 0.76 | GRM2 (0.36) | — | |
| SCHEMBL7100181 | 0.75 | PTGS1 (0.41) | PTGS2 | |
| SCHEMBL7022958 | 0.71 | GAA (0.47) | — | |
| SCHEMBL7101699 | 0.70 | ACHE (0.35) | PTGS2 | |
| SCHEMBL7171935 | 0.70 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL7174724 | 0.69 | ALDH1A1 (0.49) | — | |
| SCHEMBL6410882 | 0.68 | TDP1 (0.34) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274700-A1 | DIHYDROBENZOPYRANS, DIHYDROBENZOTHIOPYRANS, AND TETRAHYDROQUINOLINES FOR THE TREATMENT OF COX-2-MEDIATED DISORDERS | Pharmacia Corporation (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001049675-A1 | DIHYDROBENZOPYRANS, DIHYDROBENZOTHIOPYRANS, AND TETRAHYDROQUINOLINES FOR THE TREATMENT OF COX-2-MEDIATED DISORDERS | PHARMACIA CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |