Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521222 | 0.80 | ADRA2A (0.46) | MTNR1AOPRD1 | |
| Dimethylamine SCHEMBL8433452 | 0.78 | OPRD1 (0.38) | MTNR1AOPRD1 | |
| SCHEMBL7874968 | 0.75 | MTNR1A (0.44) | ACHEMTNR1A | |
| SCHEMBL2463176 | 0.75 | MTNR1A (0.60) | ACHEMTNR1A | |
| SCHEMBL25413828 | 0.75 | ACHE (0.43) | ACHEMTNR1A | |
| SCHEMBL20283375 | 0.75 | ACHE (0.44) | ACHE | |
| SCHEMBL8433448 | 0.74 | MTNR1A (0.43) | MTNR1AOPRD1 | |
| SCHEMBL7950364 | 0.74 | MTNR1A (0.41) | MTNR1A | |
| SCHEMBL5969884 | 0.74 | CA12 (0.48) | ACHEMTNR1A | |
| SCHEMBL8436852 | 0.73 | MTNR1A (0.38) | ACHEMTNR1AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923543-B1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2003-09-24 | — | — | EP | disclosed |
| US-6083986-A | Potassium channel inhibitors | ICAGEN, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0923543-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004521-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1998-02-05 | — | — | WO | disclosed |